Chinyere Aguocha1, Richard Uwakwe2, Emmanuel Olose3, Kennedy Amadi4, Gabriel Onyeama4, Chukwuma Duru5

1. Imo state university Teaching Hospital, Orlu, imo state, Nigeria, Department of Medicine;
Imo state university , owerri, imo state, Nigeria, Department of Medicine.
2. Nnamdi Azikiwe University Teaching Hospital, Mental Health.
3. Department of Psychiatry, University Of Calabar, Cross Rivers, Nigeria.
4. University of Nigeria, Department of Psychological Medicine
5. Imo State University Teaching Hospital, Orlu, Nigeria. , Community Medicine

Abstract:
Background: The chronic and debilitating nature of schizophrenia creates a disease with marked clinical and economic consequences. Smoking in schizophrenia appears to be associated with increased psychopathology and disability.
Objective: The aim of this study was to determine if cigarette smoking in schizophrenia is associated with increased disability and psychopathology.
Materials and methods: This was a cross-sectional descriptive study in which 367 out-patients with International Classification
of Diseases (ICD) 10 diagnosis of schizophrenia were recruited. Socio-demographic questionnaire, Present State Examination (PSE) 10, Positive And Negative Syndrome Scale (PANSS) and World Health Organization Disability Assessment Schedule (WHODAS) were administered. Data was analyzed using a software package SPSS version 15.
Results: There was no significant difference in the mean PANSS scores of smokers and non-smokers. Current smoking was associated with increased disability (F=5.39, p=0.02). Total PANSS score significantly predicted disability F(3,71=5.60, p=0.002, R2=0.19). There was no significant association between positive or negative symptoms and being a smoker or non-smoker.
Conclusion: The results of this study revealed that smoking in Nigerian schizophrenia patients is associated with significant
disability. Measures should be put in place to discourage cigarette smoking among Nigerian patients with schizophrenia.
Keywords: Schizophrenia, smoking, psychopathology, disability, Nigeria.

DOI: https://dx.doi.org/10.4314/ahs.v18i1.14

Cite as: Aguocha C, Uwakwe R, Olose E, Amadi K, Onyeama G, Duru C. Clinical implication of smoking among patients with Schizophrenia at a Tertiary Institution in South East Nigeria. Afri Health Sci 2018;18(1): 102-110. https://dx.doi.org/10.4314/ahs.v18i1.14

Clinical implication of smoking among patients with Schizophrenia  at a Tertiary Institution in South East Nigeria.PDF