Efficacy of combined traditional Chinese medicine spray with premature ejaculation  desensitization therapy for the treatment of primary premature ejaculation.

Ying-Dong Cui, Shu-Bin Hu, Bo Wu, Shi-Jun Li, Kui Xiang, Zhao-Lin Liao, Hui-Ping Zhang2, Chang-Hong Zhu, Meng Rao.

1. Department of Urology, Enshi Tujia and Miao Autonomous Prefecture nationality Hospital, Enshi, Hubei, China.
2. Family Planning Research Institute, Tongji Medical College, Huazhong University of Science and Technology,
Wuhan, Hubei, China.

Abstract
Objectives: We recommend a new kind of spray made from eight kinds of traditional Chinese medicine, we aimed to investigate
the safety and clinical efficacy of combined traditional Chinese medicine spray (TCMS) with premature ejaculation desensitization therapy (PEDT) for the treatment of primary premature ejaculation (PPE).

Methods: A total of 90 patients with PPE were randomly assigned to receive TCMS, PEDT monotherapy or TCMS plus PEDT
combination therapy for 6 weeks. Intravaginal ejaculation latency time (IELT) and Chinese index of sexual function for premature ejaculation (CIPE-5) were measured to evaluate the effect of each treatment.

Results: Eighty six (86) participants completed the study voluntarily. Both IELT and CIPE-5 in these three groups increased  after treatment when compared with baseline levels (p< 0.01). IELT and CIPE-5 after treatment in TCMS plus PEDT group  were significantly higher than those in the other two groups (both p <0.05). Additionally, clinical efficacy in TCMS plus PEDT  group (89.7%) was significantly higher than in TCMS (65.5%) and PEDT group (67.9%) (p< 0.01).

Conclusion: The self-made TCMS was safe and effective for the treatment of PPE, a combination of TCMS and PEDT therapy was more effective than the TCMS or PEDT monotherapy.

Keywords: Primary premature ejaculation (PPE); traditional Chinese mdicine spray (TCMS); premature ejaculation desensitization training therapy (PEDT); Intravaginal ejaculation latency time (IELT); Chinese index of sexual function for premature  ejaculation (CIPE-5). spray with premature ejaculation desensitization therapy for the treatment of primary premature ejaculation: a randomized clinical study. Afri Health